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The following section summarizes various therapeutic targets that have been clinically tested, with a focus on targeting inflammation, and discusses potential anti-inflammatory strategies for treating ALD (Fig

Since vascular growth is not only up-regulated but also accompanied by significant changes in their architecture (i.e., abnormal vasculature, disorganization, etc.) and function [129,130], a tumor burdened with those vessels may eventually be resistant to various therapeutic methods, including systemic treatment in the form of chemotherapy or radiotherapy [131]

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Iimuro Y, Bradford BU, Yamashina S, Rusyn I, Nakagami M, Enomoto N et al

Tempe, AZ, USA: 2019
