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Description
Research demonstrates that TB-500 forms functional complexes with PINCH-1 and integrin-linked kinase (ILK) that can inhibit TNF--induced NF-B activation through blocking RelA/p65 translocation, providing rapid suppression of inflammatory transcriptional programs
Asadpour, M
G.WideenL
Im a hooper. Mr
To eliminate cross-reactive antibodies, the supernatants were tested against a non-Fc protein, ICOS-L 1-268
4,000+ modulated genes
