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Description
Both Nrf1 and Nrf2 knockout mice have lower GCLC expression [114,115] and overexpression of Nrf1 and Nrf2 can induce the human GCLC promoter activity [104,116]

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H.NadaK.HondaC.KitashibaH.WenX

48, Dec

IACS-010759, a selective mitochondrial complex I inhibitor, reduces tumorigenicity in acute myeloid leukemia models dependent on oxidative phosphorylation, with enhanced efficacy under glucose-restricted conditions
