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If carnitine supplementation is coupled with supplemental intake of lysine (and to a lesser degree, methionine), a smaller dose of carnitine can be taken, which should forestall any side effects

For older adults, acetyl-L-carnitine acts as a powerful cognitive enhancer

[DOI] [PubMed] [Google Scholar] 112.Lowe DM, Alderton WK, Ellis MR, Parmar V, Miller WH, Roberts GB, et al
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R -lipoic acid is also found in the E3-binding protein (protein X component) of the pyruvate dehydrogenase complex (5)