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Description
It is noteworthy that cystine starvation has been observed to induce -glutamyl-peptide accumulation via the NFE2-like BZIP transcription factor 2 (NRF2)-glutamate-cysteine ligase catalytic subunit (GCLC) axis, thereby preventing ferroptosis in a GSH-independent manner in non-small cell lung cancer (NSCLC) cells [44]

doi: 10.1158/2326-6066.Cir-23-0083
doi: 10.1002/hep.30224

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Physical activity of the skeletal muscle is directly correlated with O 2 consumption, therefore, more intense is the exercise greater is the production of ROS/RNS

In: Pharmacology of Itch
