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Elevated inflammatory markers such as ESR and CRP often accompany active synovitis, myositis, or systemic vasculopathy, whereas their normalization may indicate disease remission or effective immunomodulation

E.WilcoxG

Metabolic flux and the regulation of mammalian cell growth

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J Anat 2003

Due to the miniaturization of the flow chambers and the limitations of the membranes, the conventional dynamic BBB models were mostly discontinued
