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Conversely, the mechanisms of sleep homeostasis are less defined but it is hypothesized that they play a role by monitoring variables that accumulate during wakefulness and triggering sleep once a certain threshold is reached (Laposky et al

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As plaques grow, lysosomal signals shift from neurons to DAM, with a corresponding reduction in lysosomal proteins within dystrophic neurites

Zorec, R., Zupanc, T
Metabolic symbiosis: nutrient exchange supporting CSCs CSCs establish metabolic symbiosis with surrounding stromal cells to ensure a continuous supply of energy substrates for survival and proliferation 311 (Fig

Selective ablation of retinoid X receptor a in hepatocytes impairs their lifespan and regenerative capacity
