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Chloroacetamide electrophiles are relatively reactive toward nucleophilic residues

By activating AMPK, GSK621 was shown to be able to cause immunogenic cell death in AML cells, hence enhancing anti-tumor immune responses

Journal of Environmental Biology, 45 (3), 259267

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These tests include SDS-PAGE and HPLC.

Figure 3 GSTP Enters the Nucleus and Interacts with HMGB1 in Response to LPS Stimulation The immunoblotting analysis and confocal microscopy observation showed that nuclear GSTP protein level can be detected within 5 min after LPS treatment and peaked at 1 h (Figures 4AC)