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Formulations of cyanocobalamin injection containing benzyl alcohol as a preservative should also be avoided in premature neonates and those with hypersensitivity due to its association with gasping syndrome

Studies have shown that when NNMTi is combined with a lowcalorie diet, the rate of body weight loss in obese mice is significantly faster than in either singleintervention group, with more pronounced reduction of adipose tissue and greater improvement in insulin sensitivity and hepatic metabolism