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For tissue analysis, approximately 0.5 g of liver tissue was homogenized in 4.5 mL of ice-cold normal saline (0.9% NaCl, 1:9 w/v) using a sterilized mortar on ice

Several reports indicate that 70% of patients with rheumatoid arthritis have decreased serum folate, with ASA-induced alterations in serum folate binding [179] (Table 1) (Figure 2)

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[] According to the same report, LA was also found to be most effective in chelating Cu 2+ , Zn 2+ and Pb 2+ , but instead was incapable of chelating Fe 3+ , while on the hand, DHLA will form complexes with Cu 2+ , Zn 2+ , Pb 2+ , Hg 2+ and Fe 2+ which are known to be poorly soluble in water