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Large-scale phosphoproteomics using a kinase inhibitor panel To demonstrate the power and scalability of the rapid DIA-based site-specific phosphoproteomics workflow developed here, we applied it to identify phosphorylation site targets of the ten major protein kinases in the epidermal growth factor signaling pathway using a panel of 30 kinase inhibitors (Fig

doi: 10.1038/jhh.2016.37 117 RichterHGHansellJARautSGiussaniDA

Consequently, cell disulfide stress ensues, ultimately leading to cell death

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They run as an interconnected system
