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Tregs promote environment conversion from pro to anti-inflammatory by releasing anti-inflammatory cytokines (for example, IL-4, IL-10, IL-13) that stimulate M1 (bactericidal and inflammatory) to M2 (immunomodulatory) macrophages phenotype exchange, apoptosis or inhibition of neutrophil inflammatory activity (Li et al., 2018)

Correspondingly, using specific carbohydrate-rich and protein-restricted diets followed by administration of vitamins (e.g., B and K) can be helpful in the suitable prevention of AFs end effects (323)

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Supplementation of diets with alpha-Tocopherol reduces serum concentrations of gamma- and Delta-Tocopherol in humans

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