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The scoring standard for IHC staining adopted the immunoreactive score (IRS) system [15, 16], with the specific rules as follows: the staining intensity of GGCT protein was classified into four grades, where a score of 0 indicated no staining signal, 1 indicated weak positivity, 2 indicated moderate positivity, and 3 indicated strong positivity

Biomed J 8:66596662

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With healthy lifestyle changes and effective treatment, many people may be able to prevent advanced-stage CKD

In this regard, precision geromedicine should take into account that the expression of metabolizing enzymes (such as cytochrome P450 isoforms) and hepatic membrane transporters are regulated, like many other genes, by clock-dependent mechanisms, and influence intestinal absorption, hepatic uptake, and biliary and renal excretion of various drugs (Zhang et al., 2009

Weight regulation involves various factors, including your intake of essential nutrients