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380 Firstly, the expression of GLP-1R is enhanced in the inflamed muscle fibers under pathological conditions, revealing the critical role of GLP-1R in regulating the muscles response to inflammation

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Cmara et al.observed that after 5 weeks of HIIT, IL-4 (Th2 cytokine) levels decreased, while the IFN-/IL-4 ratio significantly increased, indicating a shift towards Th1 cells, which enhanced CD4 + T cell autophagy and anti-apoptotic capacity, mitigating hypoxia-induced damage (119)

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