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doi: 10.1016/j.ejim.2010.05.007
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GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 auto-reactive CD4 T cells

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Moreover, some stakeholders have questioned the use of capitated managed care programs for vulnerable populations out of concern that narrower provider networks and reduced reimbursement rates may create a barrier to access and adversely affect the quality of care (Solomon, 2012)

The freeze-thaw cycle can damage the peptide's structure through the formation of ice crystals, leading to aggregation and loss of bioactivity