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The circuitry of dopamine system regulation and its disruption in schizophrenia: insights into treatment and prevention

In PD, altered Trp metabolism and disrupted AhR signaling have been observed in patients, with reductions in neuroprotective Trp metabolites frequently reported [166]

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2018;172(3):409-422 e421

It is used to treat a myriad of conditions, ranging from autism to Alzheimers disease
