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A phase I safety study in healthy adults confirmed that subcutaneous MOTS-c injections at doses up to 10 mg produced no serious adverse events, with a pharmacokinetic profile supporting once-daily or every-other-day dosing [3]

The FDA first approved it as an appetite suppressant in 1959

While oral BPC-157 formulations exist, they are primarily studied for their effects on the gastrointestinal tract

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VinuNavarroJHerrero-CerveraAGarca-CubasMAndrs-BlascoIMartnez-HervsSet alThe GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype
