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Neurochem Int 45(5):633640

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Zhang Q., Hu Q., Wang J., Miao Z., Li Z., Zhao Y., Wan B., Allen E.G., Sun M., Jin P., Xu X
Contrary to the long-lasting belief that IBS is not associated with organic changes, there is now growing evidence supporting that structural, although subtle, changes may be found in the gastrointestinal tract of large subgroups of these patients (197)

Here's what gets us excited: if a relatively small dose of oral glutathione (remember, only 20% gets absorbed) showed these benefits, imagine what IV delivery of therapeutic doses might accomplish

Glucose + 2 ADP + 2 NAD + + 2 P i 2 Pyruvate + 2 ATP + 2 NADH + 2 H + Free Energy (G o ) of Reactions of Hepatic Glycolysis free energy values were obtained from Li et al

NMN may play a role as an NAD activator / NAD precursor, a coenzyme often associated with healthy aging and longevity.*