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doi:10.1016/j.jand.2016.09.025

Butyrate produced by commensal bacteria potentiates phorbol esters induced AP-1 response in human intestinal epithelial cells

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BT from the intestine has been proposed by numerous authors in order to explain sepsis and endotoxemia observed in patients with severe trauma, burns, intestinal obstruction, pancreatitis, and acute liver diseases [4, 58]

Research on MOTS-c in ovariectomized mice (a model for postmenopausal metabolic dysfunction) showed reduced fat accumulation in white adipose tissue, increased brown fat activation, and improved insulin sensitivity after just 5 weeks of treatment