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Very soluble in water, ethanol and methanol, slightly soluble in acetone, insoluble in ether, benzene, chloroform and ethyl acetate

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5.3 Therapeutic Implications A detailed understanding of steroidogenesis has informed multiple therapeutic strategies, including aromatase inhibitors for estrogen-sensitive breast cancer, 5-reductase inhibitors for benign prostatic hyperplasia, glucocorticoid replacement for adrenal insufficiency, and mineralocorticoid receptor antagonists for hypertension and heart failure