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Long-chain fatty acids are activated to acyl-CoA in the cytosol, transported into mitochondria via the carnitine shuttle, and undergo sequential -oxidation to generate acetyl-CoA, nicotinamide adenine dinucleotide hydride (NADH), and reduced flavin adenine dinucleotide (FADH 2 )

Editorial Information Editor-in-Chief Yeun-Hwa Gu Junshin Gakuen University, Japan Article type Review Article Publication History Received: April 05, 2021 Accepted: May 02, 2021 Published: May 09, 2021 Copyright 2021 Mller KE

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The effects produced by other NSAIDs are reversible & are time-dependent (they depend on the pharmacokinetics and dosing intervals of each particular NSAID)