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Pediatr Nephrol 7:159162

However, under conditions where reverse cholesterol transport capacity is reduced or where emigration of macrophages is inhibited, uptake of oxLDL by macrophages leads to its accumulation and initiation of pathophysiological processes

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found that the phosphorylation of Ser1102 on AF-6 occurs by AMPKs promotion of afadin-mediated ZO-1 assembly