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Optimal timing involves fasted-state administration (06:0009:00) when beta-3 receptor sensitivity peaks, ideally 3045 minutes before moderate-intensity aerobic exercise to ensure mobilised fatty acids are oxidised rather than re-esterified

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Doctors may prescribe it for adults with obesity (a BMI of 30 or higher) or those who are overweight (a BMI of 27 or higher) and have other medical conditions such as diabetes, hypertension, and hypercholesterolemia

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[DOI] [PubMed] [Google Scholar] 173.Bilic Z., Gojkovic S., Kalogjera L., Krezic I., Malekinusic D., Knezevic M., Sever M., Lojo N., Kokot A., Kasnik K., et al