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Description
Spots from B12 is common

Ugamraj HS, Dang K, Ouisse L-H, Buelow B, Chini EN, Castello G, et al

10.4068/cmj.2015.51.2.58

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A B12 injections effect can last anywhere from a couple of weeks to a few months, and the difference comes down to why you are deficient, how well your body holds on to B12, and the dose and schedule you are on
The half-life of tirzepatide is approximately 5 days, so the effects are essentially continuous throughout the week regardless of when you inject
