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179 Three additional observational studies were retrieved in the 2014 update literature review

It is characterized by the loss of dopamine-producing cells in the brain, leading to motor dysfunction, tremors, and cognitive decline

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Of the 16 genes whose expression changed only after GABA administration (1-h time point), 11 showed reduction in mRNA expression, in particular Junb and Gabrd (2.8 and 2.7 times, respectively)

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