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Zhang Y, Liu Jbo, Liu J, Liu M, Liu Hli, Zhang J

doi: 10.1038/s41467-020-15646-6 144 DodsonMCastro-PortuguezRZhangDD

They achieve this multifunctionality by expression of a diverse set of activation receptors, including those that directly recognize pathogens and opsonized targets, and by their ability to store and release preformed cytotoxic mediators that participate in host defense, to produce a variety of de novo pleotropic mediators and cytokines, and to interact directly and indirectly with diverse cell types, including adaptive and innate immunocytes and structural cells

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For instance, polymeric nanoparticles (PNPs), lipid nanoparticles (LNPs), and nanogels can encapsulate glabridin effectively, enhancing its water solubility and controlling drug release

Thus, higher GSSG/GSH ratio indicates increased oxidative stress