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For patients with unexplained mental and motor developmental delay, seizures, recurrent acute encephalopathy, and systemic multisystem manifestations, it is important to conduct early diagnostic investigations such as cranial MRI, EEG, plasma amino acid metabolism, urine organic acid metabolism analysis, CSF metabolism, and genetic testing to clarify the diagnosis

Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress

Rates were normalized for relative GSTP1 levels estimated by densitometry, with bars representing means (SD) of three independent experiments

Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease

Age-related inflammation and insulin resistance: A review of their intricate interdependency

Dabei werden die Fremdstoffe in zwei Phasen umgewandelt: In Phase I werden sie durch Oxidation, Reduktion oder Hydrolyse chemisch verndert