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366 doi: (Published 18 September 2019) Cite this as: BMJ 2019;366:l4966 Neeti Ghali, consultant clinical geneticist1, Glenda Sobey, consultant dermatologist and clinical lead2, Nigel Burrows, consultant dermatologist3 1 North West Thames Regional Genetics Service and National EDS Service, London North West University Healthcare NHS Trust, Harrow HA1 3UJ, UK 2 National EDS Service, Sheffield Children's NHS Foundation Trust, Sheffield, UK 3 Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK Correspondence to: N Ghali neeti nhs nhs.net What you need to know Ehlers-Danlos syndromes (EDS) are inherited connective tissue disorders with variable severity