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This article points out the benefits of B12 injections and how long they can last

Observational studies A large number of cross-sectional and prospective cohort studies have associated elevated blood homocysteine concentrations with measures of poor cognitive scores and increased risk of dementia, including Alzheimer's disease (reviewed in 67, 69)

The rubber stopper is coring If small pieces of rubber break off into the vial when you insert the needle, you are using a needle that is too large or inserting it incorrectly

Mechanical Pretreatment

And so, this brings back our question: How long does a B12 shot last and stay in your system

Be sure to rotate injection sites to avoid using the same spot each time to avoid injection site reactions