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However, this can take a couple of weeks of consistent intake of B12

[16] [121] Investigations into the intestinal absorption of B 12 confirm that the upper limit of absorption per single oral dose is about 1.5 g, with 50% efficiency

See these diagrams: Source: Clinical Procedures for Safer Patient Care by Doyle & McCutcheon

For adult off-label use, typical daily doses often range from 0.2 mg (200 mcg) to 0.5 mg (500 mcg)

However, researchers acknowledge they are far from developing a clinical application

While individual results may vary, many report immediate alleviation of symptoms lasting for several months