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10.1111/j.1464-410X.2011.10860.x 60 GalloM.FormatoA.CiaravoloM.LangellaC.CataldoR.NaviglioD

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Therefore, silibinin offers significant promise as a therapeutic agent in reversing tumor drug resistance through various mechanisms, including inhibition of drug efflux pumps, modulation of cell adhesion, and regulation of key signaling pathways like STAT3
However, mechanisms, underlying the partial agonistic effect and the bell-shaped curve evoked by GSB-106 require further investigations

Another meta-analysis, published in 2021, examined the results of six SGLT2 inhibitor trials that included nearly 47,000 subjects with type 2 diabetes, about 31,000 of whom had atherosclerotic cardiovascular disease
