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10.1016/j.molcel.2017.06.008 111 SooriyaarachchiM.GeorgeG

L., Asthana, S., Tihan, T., DeRisi, J

32 Although traditionally muscle cramps have been considered most common in neuropathies with a high burden of motor or large fiber involvement, muscle cramps have also been observed with similar frequency in people with predominantly sensory or small fiber neuropathies
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Simultaneously, chronic low-grade inflammation mediated by NF-B activation and elevated cytokines including TNF- and IL-6 independently impairs the insulin receptor via serine phosphorylation of IRS-1

Alterations in HLA and complement pathway deficiencies also play a crucial role in SLE development

Moallaei H, Bouchara J-P, Rad A, Singh P, Raizada P, Tran HN, et al
