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Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 3

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Firdus et al., 2022)

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10.1016/j.intimp.2023.111453 258 ZhangW.LiuY.LiaoY.ZhuC.ZouZ

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Research indicates that the introduction of epoxy groups primarily inhibits apoptosis by stabilizing mitochondrial function, while functional groups such as carboxyl, carbonyl, or hydroxyl groups act as secondary pharmacophores, significantly enhancing free radical scavenging efficiency through electron delocalization effects ( The protective effect of rhodioloside, the primary component of Rhodiola crenulata (Hook

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