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[PubMed] [Google Scholar] Jaeschke H

The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis

A study by Hu et al

BPC-157 (Body Protection Compound-157), also designated as PL 14736, is a synthetic pentadecapeptide composed of 15 amino acids (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) that was first isolated and identified from human gastric juice in the early 1990s

However, this same GPR model also delivers the least accurate predictions for the 22 compounds of the external test set with an RMSEP of 0.59 and a MAE of 0.43, possibly indicative of overfitting to the training set data

It is a cyclic derivative of gamma-aminobutyric acid (GABA) and acetamide