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Compared with controls, adherent SC-islets treated with ZnPTO exhibited a higher proportion of EGFP + GCG + cells, supporting the hypothesis that excessive zinc induces the conversion of SC- cells into SC- cells (Supplementary information, Fig

Researchers have genetically engineered insulin fusion proteins capable of targeting hippocampal neurons

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During states of increased systemic inflammation, such as sepsis or trauma, the brain experiences a mismatch between energy supply and demand, which is commonly associated with delirium in those with preexisting cognitive impairment [3]

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For instance, it has been reported that imatinib, nilotinib, and ponatinib reversed the P-gp-, ABCG2-, and ABCC10-mediated MDR by inhibiting their efflux activity (Kathawala et al., 2015