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In tissues, the ketosteroid isomerase reactions catalyzed by GSTs are strictly dependent on dehydrogenases such as 3-hydroxysteroid dehydrogenase and 17-hydroxysteroid dehydrogenase for production of the 3-keto substrates from the corresponding 3-hydroxysteroid precursors, since the GSTs are lacking dehydrogenase activity
There is a higher risk for sepsis, acute respiratory failure, acute renal failure, prolonged ICU stay, as well as increased mortality and morbidity for patients with vitamin D deficiency ( 2.3
Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells
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The loss of GSH disrupts redox homeostasis, leading to ROS accumulation and, subsequently, cellular dysfunction and death [10]
