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Topical Cream Application Instructions Cleanse the face gently and pat dry before applying Apply a small, pea-sized amount (approximately 0.5 mL or as directed by the prescriber) evenly across the face, avoiding the immediate eye area, nostrils, and corners of the mouth Apply once daily in the evening tretinoin is photosensitive and is best used at night Allow the cream to absorb fully before applying any additional moisturizer or sunscreen Apply a broad-spectrum sunscreen of SPF 30 or higher every morning without exception tretinoin and estriol increase photosensitivity, and sun protection is essential to address potential irritation and hyperpigmentation Start slowly: if new to tretinoin, apply every other night for the first 24 weeks, then advance to nightly use as tolerated Do not apply to broken, sunburned, irritated, or actively inflamed skin Avoid contact with the eyes, lips, and mucous membranes

doi: 10.1002/ajmg.b.32728 63

It also nourishes the skin with acai berry extract, helping the skin look younger

Gi thnh l 450,000 ng vi hp 2 l x 30 vin

Data availability Data sharing does not apply to this review article