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Body composition may influence dosing requirements, though weight-based dosing has not been consistently employed in animal studies or limited human applications

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Timing matters: take oral B12 supplements at least two hours apart from any other medications, and consider sublingual lozenges or liquid formulations, which allow some absorption through the mouth lining and bypass the stomach entirely

Cyanocobalamin is the cheap, synthetic form of B12 that requires your body to convert it before use, while methylcobalamin is the active, pre-converted form your cells can use immediately