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It is now well-established that neuroinflammation promotes the pathogenesis of AD and other neurodegenerative diseases (246)

This method has been proven to be in conformance with FDA Guideline Guidance for IndustryBioanalytical Method Validation (May 2001) 111 , which implies proof of reproducibility within a given error range
[DOI] [PMC free article] [PubMed] [Google Scholar] 171.Martn-Rodrguez JF, Ramos-Herrero VD, Parras GG, Flores-Martnez , Madrazo-Atutxa A, Cano DA, et al
Coffee polyphenols exert hypocholesterolemic effects in zebrafish fed a high-cholesterol diet

Numerous studies have examined homocysteine levels to determine whether vitamin B12 deficiency occurs at the tissue level [2,3,19-21]
