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doi: 10.1016/s0047-6374(97)01897-6
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In vitro, 5-Amino-1MQ at 30 M in 3T3-L1 adipocytes significantly reduced intracellular 1-MNA levels, confirming NNMT target engagement

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(2013) 144:142637:37 e19

A small pilot study using prospective data from 13 women, between 6683 years, living with obesity and prescribed orlistat, found weight loss of 9.4% over 6 months [105]