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Childhood obesity has been linked to epigenetic changes in umbilical cord tissue, among other later effects

The leap from animal model findings to confirmed human benefit is significant, and many compounds that show promise in preclinical research do not translate successfully to human medicine

[DOI] [PubMed] [Google Scholar] [67].Fieten H, Gill Y, Martin AJ, et al

Nagle CM, Dixon SC, Jensen A, Kjaer SK, Modugno F, deFazio A, Fereday S, Hung J, Johnatty SE, Fasching PA, Beckmann MW, Lambrechts D, Vergote I, Van Nieuwenhuysen E, Lambrechts S, Risch HA, Rossing MA, Doherty JA, Wicklund KG, Chang-Claude J, Goodman MT, Ness RB, Moysich K, Heitz F, du Bois A, Harter P, Schwaab I, Matsuo K, Hosono S, Goode EL, Vierkant RA, Larson MC, Fridley BL, Hgdall C, Schildkraut JM, Weber RP, Cramer DW, Terry KL, Bandera EV, Paddock L, Rodriguez-Rodriguez L, Wentzensen N, Yang HP, Brinton LA, Lissowska J, Hgdall E, Lundvall L, Whittemore A, McGuire V, Sieh W, Rothstein J, Sutphen R, Anton-Culver H, Ziogas A, Pearce CL, Wu AH, Webb PM (2015) Obesity and survival among women with ovarian cancer: results from the ovarian cancer association consortium

[5] Post introduction, it is suggested that IGF-I levels could remain elevated for at least 2 weeks in test models receiving greater exposure

WS may act as a drug of choice in such cases (Clinical Management Protocol 2020) (Rawat and Bisht, 2014) (Owais et al., 2005)