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15 It may be initially treated with glucose supplementation orally or via IV

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An experiment confirmed that trimetazidine increased the levels of ketone metabolism-related proteins in heart failure rats and reduced ketone levels after treatment, improving pathological cardiac remodeling (Li H

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In hypogonadal men with diabetes or in male rodents with androgen deficiency, decreased mitochondrial density, abnormal mitochondrial morphology, and lower ATP production were observed, while exogenous testosterone supplementation effectively alleviated mitochondrial dysfunction and improved glucose and lipid metabolism ( 2 The sex-dimorphic regulatory impact of androgens and AR on glucose and lipid metabolism 2.1 Inhibited androgens/AR negatively affects glucose and lipid metabolism in males The most well-known androgens include testosterone, androstenedione, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and dihydrotestosterone (DHT)