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The neuronal pathological changes were also observed in the acquired digital images saved as uncompressed 24-bit RGB TIFF files in the software program AnalySIS (Olympus Soft Imaging System GmbH, Mnster, Germany) performing quantitative analysis of neuronal damage in the karyopyknotic areas

J Clin Oncol 20 : 19231931 Estlin EJ, Pinkerton CR, Lewis IJ, Lashford L, McDowell H, Morland B, Kohler J, Newell DR, Boddy AV, Taylor GA, Price L, Ablett S, Hobson R, Pitsiladis M, Brampton M, Clendeninn N, Johnston A, Pearson AD (2001) A phase I study of nolatrexed dihydrochloride in children with advanced cancer
