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In Alzheimer disease specifically, BDNF deficits are most pronounced in the hippocampus, entorhinal cortex, and prefrontal cortex, the regions earliest and hardest hit by the disease
& Cousins, R
For individuals with conditions like diabetic neuropathy or other nerve-related issues, B12 injections can help alleviate symptoms such as tingling, numbness, or pain
doi: 10.1016/j.bbabio.2003.06.008
The scale-up of small-molecule manufacturing is also fundamentally more straightforward than peptide scale-up
Endotext (2019)
