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1994) constitute the most widely used model in ALS preclinical research
Although increased sampling (number of stools) and diagnostic (number of examinations per stool) efforts can improve sensitivity, Kato-Katz is less sensitive than other microscopy methods such as FLOTAC

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Respirology 14(7):917933

In addition, NAC has the potential to interact directly with oxidants or regulate the activation of nuclear factor (NF)-B and hypoxia-inducible factor-1 (HIF-1) to attenuate acute lung injury
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