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The term scatter factor was later introduced independently in 1985 by Stoker and co-workers, as they discovered a protein interrupting the intracellular junctions of epithelial cells thereby promoting their migration in a paracrine manner and promoting an invasive phenotype [4]

Additionally, ATF3 regulates genes such as acyl-CoA synthetase long chain family member 4 and lipoxygenases, essential for producing and incorporating PUFAs into cellular membranes, which is a critical step in lipid peroxidation (119121)

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Nitric oxide pathway modulation: BPC-157 interacts with the NO system, which influences vascular tone, platelet aggregation, and gut mucosal integrity