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In skeletal muscle, SIRT1 is thought to promote mitochondrial biogenesis through the deacetylation of PGC-1 in fasting conditions and promote mitophagy by targeting mitophagic machinery (Palikaras et al., 2015)

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26 LiL.LiM.LuJ.GeX.XieW.WangZ.et al (2018)

doi: 10.1101/gad.10.2.165

Cubillos-Ruiz, A

Kishi Y, Kopetz S , Chun YS, Palavecino M, Abdalla EK, Vauthey JN