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Conversely, VTA DA neurons, which are less vulnerable than SNpc DA neurons, generate broad spikes and are autonomous pacemakers, but have smaller Cav1 channel currents and a strong intrinsic calcium buffering by calbindin

Abstract Bloodbrain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood

In conclusion, our results identify CP as a potential therapeutic target to protect dopaminergic neurons by reducing neurons sensitivity to ferroptosis

This broad-spectrum activity makes natural products well-suited to address the multifactorial nature of AD (Chen et al., 2021)

In addition, a curated subset of neutrophil granule proteins was analyzed separately to highlight their abundance patterns across inhibitor treatments

The liver utilizes a critical two-step process known as Phase I and Phase II detoxification