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A significant increase in NQO1 occurred between 6 and 12 hours, a timeframe that may not be sufficiently responsive for management of an acute state, leaving one to conclude that NQO1 induction is best suited to chronic conditions where a rapid response may not be necessary
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Thomson CA, Chow HHS, Wertheim BC, et al
& Mohandas, N
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Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
In COPD, there is a shift toward M1 phenotype (121)
