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Sleep Med Rev 4(3):253262 Riemann D et al (2010) The hyperarousal model of insomnia: a review of the concept and its evidence

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in-depth research on the regulatory mechanisms of ferroptosis and the role of ferroptosis in RA is expected to lead to the development of more precise and efficient ferroptosis-targeted therapeutic strategies for RA

This does not rule out a significant role of IGF-I being produced either systematically or locally

Future nanoparticle studies may therefore need to consider risk-adapted approaches, including lower starting doses, gradual dose escalation, patient stratification based on genetic, vascular and imaging biomarkers, and serial neuroimaging surveillance (Lee et al., 2026)

Graphic abstract A novel one - pot synthesis for in situ functionalized hydrophilic magnetite nanoparticles at atmospheric pressure and a temperature lower than 200 C for Magnetic Resonance Imaging applications is reported